HUBUNGAN JUMLAH LEUKOSIT DENGAN MOTILITAS SPERMATOZOA PADA ANALISIS SEMEN PRIA DI SAMMARIE FAMILY HEALTHCARE 2019

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Wanodia Ayutama
Tuty Rizkianti
Cut Fauziah

Abstract

Infertility is one of the most common male reproductive health problems. Male infertility is the inability of a male to result pregnancy in a fertile female in one year of non-contracepting sexual intercourse. Male with poor sperm quality are more susceptible to infertility. One of the cause of infertility in men is disruption of spermatozoa motility. Imperfect motility will reduce the quality of spermatozoa and the probability of conception. One cause of decreased motility is inflammation of the male reproductive tract. Inflammation that occurs will increase the recruitment of leukocytes in the reproductive tract and increase the production of reactive oxygen species (ROS) so it can interfere the process of sperm formation and maturation. The purpose of this study was to determine the relationship between leukocyte counts and spermatozoa motility. The number of leukocytes and the percentage of spermatozoa motility were obtained from semen analysis as secondary data. The research design used was cross-sectional. The number of samples in this study were 66 respondents who met the inclusion criteria.The results of the study showed a significant inverse relationship (negative correlation) (p = 0.007, r = -0.328) between the number of leukocytes and spermatozoa motility, which means  if the number of semen leukocytes increases, the percentage of spermatozoa motility will decrease.

 

Keywords: inflammation; leukocyte counts; spermatozoa motility

 

ABSTRAK

Infertilitas merupakan salah satu masalah kesehatan reproduksi pria yang sering dijumpai. Infertilitas pada pria adalah ketidakmampuan seorang pria untuk menyebabkan kehamilan pada seorang wanita fertil setelah satu tahun hubungan seksual tanpa alat kontrasepsi. Pria dengan kualitas sperma yang kurang baik lebih rentan mengalami infertilitas. Salah satu penyebab infertilitas pada pria adalah gangguan pada motilitas spermatozoa. Motilitas yang kurang sempurna akan menyebabkan penurunan kualitas spermatozoa dan penurunan probabilitas terjadinya pembuahan. Salah satu penyebab penurunan motilitas adalah inflamasi pada saluran reproduksi pria. Inflamasi yang terjadi akan meningkatkan rekruitmen leukosit pada saluran  reproduksi pria dan meningkatkan produksi reactive oxygen species (ROS) yang bersifat toksik bagi spermatozoa sehingga dapat mengganggu proses pembentukan dan pematangan spermatozoa. Tujuan penelitian ini adalah untuk mengetahui hubungan antara jumlah leukosit dengan motilitas spermatozoa. Jumlah leukosit dan persentase motilitas spermatozoa didapatkan dari data sekunder, yaitu data hasil analisis semen. Desain penelitian yang digunakan adalah potong lintang (cross-sectional). Jumlah sampel dalam penelitian ini sebanyak 81 pasien yang memenuhi kriteria inklusi. Hasil dari penelitian menunjukkan terdapat hubungan terbalik (korelasi negatif) yang bermakna dengan kekuatan korelasi sangat lemah (p = 0.007, r = -0.328) antara jumlah leukosit dengan motilitas spermatozoa, yang berarti jika jumlah leukosit semen semakin meningkat, maka persentase motilitas spermatozoa akan semakin rendah.

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