GAMBARAN KLINIS DAN HISTOPATOLOGI KASUS-KASUS ABNORMAL UTERINE BLEEDING DI RUMAH SAKIT SUMBER WARAS

Andriana Kumala Dewi, Sony Sugiharto, Anthony Paulo Sunjaya, Angela Felicia Sunjaya
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Abstract

Abnormal Bleeding Uterine Problems (AUB) is the most common disorder found in daily gynecological practice. AUB can occur at any age between menarche and menopause, but this disorder is more often found during the beginning and the end of ovarian function. Two-thirds of women who are hospitalized with abnormal uterine bleeding are over 40 years old. The causes of AUB are broadly divided into 2 namely structural and non-structural abnormalities. Diagnosis and management of abnormal uterine bleeding is currently a challenge in the field of gynecology because complaints of vaginal bleeding are the most common complaints that bring patients to health facilities. This study aims to find any histopathological features that are often found in patients with a diagnosis of AUB. This research method is a cross-sectional retrospective. Obtained 87 patients diagnosed with abnormal AUB who performed operative management during the period January to December 2018 from the Sumber Waras Hospital Polyclinic. The results of laboratory tests before the treatment showed that the majority of patients (59.8%) had anemia with an average hemoglobin of 10.79 (± 2.40) mg / dL. In the majority of patients with AUB (66.9%) the procedure was performed in the form of a biopsy/curette of the endometrial tissue for anatomical pathology. Meanwhile, based on the results obtained by the histopathological picture, found in the majority of patients found a picture of structural pathology (PALM) that is 86.2%

ABSTRAK:

Masalah  Abnormal Uterine Bleeding (AUB)  merupakan  kelainan  yang  paling  sering ditemukan  dalam  praktik ginekologi  sehari-hari. AUB dapat terjadi pada setiap umur antara menarche dan menopause, tetapi kelainan ini lebih sering dijumpai sewaktu masa permulaan dan masa akhir fungsi ovarium. Dua pertiga dari perempuan yang dirawat di rumah sakit dengan keluhan perdarahan uterus abnormal berumur diatas 40 tahun. Penyebab AUB secara garis besar dibagi menjadi 2 yaitu kelainan struktural dan non struktural. Diagnosis dan manajemen dari perdarahan uterus abnormal saat ini menjadi suatu tantangan dalam bidang ginekologi karena keluhan perdarahan per vaginal adalah keluhan tersering yang membawa pasien datan ke fasilitas kesehatan. Penelitian ini bertujuan untuk menemukan gambaran histopatologis apa saja yang sering ditemukan pada pasien dengan diagnosis AUB. Metode penelitian ini adalah cross sectional retrospective. Diperoleh 87 pasien yang didiagnosis menderita abnormal AUB yang dilakukan tatalaksana secara operatif selama periode Januari sampai Desember 2018 dari Poliklinik RS Sumber Waras. Hasil pemeriksaan laboratorium sebelum tindakan menunjukkan bahwa mayoritas pasien (59.8%) menderita anemia dengan rerata hemoglobin 10.79 (±2.40) mg/dL Pada sebagian besar pasien dengan AUB (66.9%) tindakan yang dilakukan berupa biopsi/kuret jaringan endometrium untuk pemeriksaan patologi anatomi. Sedangkan, berdasar hasil gambaran histopatologis yang didapat, ditemukan pada mayoritas pasien ditemukan gambaran patologi struktural (PALM) yaitu 86,2%.

Keywords

abnormal uterine bleeding; PALM COEIN; leiomyoma, adenomyosis; ovulation dysfunction;;abnormal uterine bleeding PALM COEIN; leiomyoma; adenomysosis; disfungsi ovulasi

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